Equipment

Key equipment

	Affymetrix Genechip system Genechip Scanner 3000 + Autoloader 7G field upgrade for 500K SNP arrays 2x Fluidic Station 450 2x Hybridisation Oven 640 Affymetrix Software: GCOS, GDAS, GTYPE, CNAT 3rd party Software: CNAG, Genespring, MatLab
	Genemachines Omnigrid 100 Genomic SolutionsTM ServerArm for handling 72 plates 48 SMP3 pins 100 slides
	GeneTAC Hybridisation stations (2 available) Genomic SolutionsTM 6 modules of 2 slides 5 solutions can be used 120µl hybridisation volume
	Axon 4200AL microarray scanner 36 slide autoloader 4 colour lasers 488, 532, 594, 635nm Analysis Software: Genepix Pro 5 and 6
	Agilent Bioanalyzer 2100
	Nanodrops ND1000 2 available

Additional equipment

Microarray Scanner	GMS428	Affymetrix
UV Crosslinker	Stratalinker 2400	Stratagene
Mikrodismembrator		Sartorius

Microarrays available

1. For genome copy number profiling we use the tiling resolution 32k BAC array, covering the entire human genome with a 100 kb resolution. This set is amplified by DOP-PCR and spotted in-house. We can print the entire set on one microarray slide or produce chromosome-specific arrays.
2. For linkage and association studies by high-density SNP profiling we use Affymetrix 10k and 100k SNP arrays (500k available at the end of 2005).
3. For expression studies we use all available Affymetrix chips, including the Genechip human genome U133 plus 2.0 array containing over 47,000 human transcripts and variants.

Next to the standard expression and SNP microarrays Affymetrix also offers a wide range of custom services. For an overview of all available Affymetrix chips please go to their website or contact us.